Molecular determinants for antibody binding on group 1 house dust mite allergens. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Molecular determinants for antibody binding on group 1 house dust mite allergens.

Dataset

identifier:	1931584
description:	epitope description:E111, D113, R115, Q116, R118, G253, R254, A278, Q279, Y283, D296, Y299, Y301 antigen name:Der p 1 host organism:Mus musculus BALB/c antibody name:4C1
aggregation:	instance of dataset
availability:	available
primaryPublications:	22210776

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022877
landingPage:	http://www.iedb.org/assay/1931584

Publication

type:	Literature
publicationVenue:	J Biol Chem
dates:	2012

Dimension

study type:	b cell assays
subject species:	Dermatophagoides pteronyssinus

Person

fullName:	Maksymilian Chruszcz Anna Pomé s Jill Glesner Lisa D Vailes Tomasz Osinski Przemyslaw J Porebski Karolina A Majorek Peter W Heymann Thomas A E Platts-Mills Wladek Minor Martin D Chapman

Data Type

method:	calorimetry

Study

name:	Molecular determinants for antibody binding on group 1 house dust mite allergens.
description:	The dissociation constant of epitope-specific Fab 4C1 binding to Der f 1 and Der p 1 was determined by isothermal titration calorimetry. Fab 4C1 bound Der f 1 and Der p 1 with similar affinity.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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