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identifier: 1934742
description:
epitope description:EAPNVPLHRS
antigen name:Transcriptional regulator ICP22 homolog
host organism:Mus musculus BALB/c
antibody name:rec-Ab 63P4
aggregation:
instance of dataset
availability:
available
primaryPublications: 22438547
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1023085
landingPage: http://www.iedb.org/assay/1934742
type:
Literature
publicationVenue:
J Virol
dates:
2012
study type: b cell assays
subject species: Human alphaherpesvirus 3
fullName:
Niklaus H Mueller
Nathan L Bos
Scott Seitz
Mary Wellish
Ravi Mahalingam
Don Gilden
Randall J Cohrs
method:
western blot
name:
Recombinant monoclonal antibody recognizes a unique epitope on varicella-zoster virus immediate-early 63 protein.
description:
The epitope was identified by truncation studies. The epitope-specific Ab reacted with the affinity-purified full-length Varicella-Zoster Virus IE63 protein. Alanine substitution of either the first 5 amino acids (E1A to V5A) or the last 5 amino acids (P6A to S10A) (lane 6) eliminated rec-MAb 63P4 binding.

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