IgE epitopes of intact and digested Ara h 1: a comparative study in humans and rats. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

IgE epitopes of intact and digested Ara h 1: a comparative study in humans and rats.

Dataset

identifier:	1937698
description:	epitope description:SPIISHY host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	22555070

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1024166
landingPage:	http://www.iedb.org/assay/1937698

Publication

type:	Literature
publicationVenue:	Mol Immunol
dates:	2012

Dimension

study type:	b cell assays
subject species:

Person

fullName:	K L Bø gh H Nielsen C B Madsen E N C Mills N Rigby T Eiwegger Z Szé pfalusi E L Roggen

Data Type

method:	phage display

Study

name:	IgE epitopes of intact and digested Ara h 1: a comparative study in humans and rats.
description:	The epitope was selected from a phage-displayed random hepta-mer peptide library using serum IgE from peanut allergic patients. For positive selection, the phages were eluted with intact or digested Ara h 1. The epitope was mapped onto the surface of a model of Ara h 1. The epitope was mapped to residues S262, P261, I260, I265, S266, H223, Y267.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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