Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1942852 |
| description: |
epitope description:beta-D-mannopyranosyl-(1->2)-beta-D-mannopyranosyl-(1->2)-beta-D-mannopyranosyl group
antigen name:(1->2)-beta-D-mannan
host organism:Mus musculus BALB/cByJ
antibody name:C3.1
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
22493450 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1024406 |
| landingPage: |
http://www.iedb.org/assay/1942852 |
| type: |
Literature
|
| publicationVenue: |
J Biol Chem
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Candida albicans |
| fullName: |
Margaret A Johnson
Jonathan Cartmell
Nina E Weisser
Robert J Woods
David R Bundle
|
| method: |
nuclear magnetic resonance (NMR)
|
| name: |
Molecular recognition of Candida albicans (1->2)-beta-mannan oligosaccharides by a protective monoclonal antibody reveals the immunodominance of internal saccharide residues.
|
| description: |
The STDD-NMR and Tr-NOESY experiments of the epitope-mAb complex showed the strongest enhancements in the reducing-end mannose residue of the epitope. Similar results were found for the complex with the mAb scFv fragment.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
