Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis.

Title:

Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis.

Dataset

identifier:	1939322
description:	epitope description:VKEFFNGKEPSRGINPDEAV + CITR(R12) antigen name:78 kDa glucose-regulated protein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	22108001

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022946
landingPage:	http://www.iedb.org/assay/1939322

Publication

type:	Literature
publicationVenue:	Arthritis Res Ther
dates:	2011

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Hirofumi Shoda Keishi Fujio Mihoko Shibuya Tomohisa Okamura Shuji Sumitomo Akiko Okamoto Tetsuji Sawada Kazuhiko Yamamoto

Data Type

method:	ELISA

Study

name:	Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis.
description:	Serum samples from RA patients with high anti-citBiP antibody levels reacted weakly with the citrullinated epitope compared to sera from healthy controls which did not react.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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