Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1024412 |
| landingPage: |
http://www.iedb.org/assay/1943173 |
| type: |
Literature
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| publicationVenue: |
PLoS One
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| dates: |
2012
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| study type: | b cell assays |
| subject species: | H5N1 subtype |
| fullName: |
Zhiliang Cao
Jiazi Meng
Xingxing Li
Ruiping Wu
Yanxin Huang
Yuxian He
|
| method: |
ELISA
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| name: |
The epitope and neutralization mechanism of AVFluIgG01, a broad-reactive human monoclonal antibody against H5N1 influenza virus.
|
| description: |
The epitope-specific mAb bound to recombinant WT HA protein in ELISA, IFA, and FACS. The residues important for mAb binding were determined with HA mutants carrying single amino acid substitutions. Binding was abolished when reduced HA was assayed, indicating that the epitope is conformational.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
