Immunological Data Discovery Index
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identifier: 1940203
description:
epitope description:T501, F502, V503, L504, K505, K506, E507, V508, E521, K523, K557, K581, L583, K584, I585, N586, W587
antigen name:Genome polyprotein
host organism:Mus musculus BALB/c
antibody name:4E11
aggregation:
instance of dataset
availability:
available
primaryPublications: 22285214
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1024470
landingPage: http://www.iedb.org/assay/1940203
type:
Literature
publicationVenue:
Structure
dates:
2012
study type: b cell assays
subject species: Dengue virus 3 Thailand/PaH881/1988
fullName:
Joseph J B Cockburn
M Erika Navarro Sanchez
Nickolas Fretes
Agathe Urvoas
Isabelle Staropoli
Carlos M Kikuti
Lark L Coffey
Fernando Arenzana Seisdedos
Hugues Bedouelle
Felix A Rey
method:
biological activity
name:
Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody.
description:
The epitope-specific mAb 4E11 neutralized Dengue virus 3 strain Thailand/PaH881/1988, as measured by flow cytometry of infected Huh7.5 cells. MAb 4E11 neutralized Dengue virus serotypes 1 and 2 better than serotypes 3 and 4.

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