Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | The structural basis for serotype-specific neutralization of dengue virus by a human antibody. |
| identifier: | 1940582 |
| description: |
epitope description:T331, N332, Q411, Y412, L415, K416, G439, T440, T445, P446, Q447, E452, I453, L455, G554, T555, L588, K590, E664, K665
antigen name:Genome polyprotein
host organism:Homo sapiens
antibody name:HM14c10
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
22723463 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1024472 |
| landingPage: |
http://www.iedb.org/assay/1940582 |
| type: |
Literature
|
| publicationVenue: |
Sci Transl Med
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Dengue virus 1 PVP159 |
| fullName: |
Ee Ping Teoh
Petra Kukkaro
En Wei Teo
Angeline P C Lim
Tze Tong Tan
Andy Yip
Wouter Schul
Myint Aung
Victor A Kostyuchenko
Yee Sin Leo
Soh Ha Chan
Kenneth G C Smith
Annie Hoi Yi Chan
Gang Zou
Eng Eong Ooi
D Michael Kemeny
Grace K Tan
Jowin K W Ng
Mah Lee Ng
Sylvie Alonso
Dale Fisher
Pei-Yong Shi
Brendon J Hanson
Shee-Mei Lok
Paul A MacAry
|
| method: |
ELISA
|
| name: |
The structural basis for serotype-specific neutralization of dengue virus by a human antibody.
|
| description: |
The epitope-specific mAb HM14c10 bound to Dengue virus serotype 1, but not to serotypes 2, 3, or 4. MAb HM14c10 bound to DENV1 of all genotypes 1, 2, 3, 4, and 5.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |