Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1943428 |
| description: |
epitope description:Q3, L5, T39, G40, K41, R44, K108, N145, I174, N175, H176, S177, S204, L205, I215, E217, Y219, R220, N221, Y223, K224
antigen name:Cell surface-binding protein
host organism:Mus musculus BALB/c
antibody name:LA5
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| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
22623786 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1024560 |
| landingPage: |
http://www.iedb.org/assay/1943428 |
| type: |
Literature
|
| publicationVenue: |
J Virol
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Vaccinia virus Acambis 2000 |
| fullName: |
Michael H Matho
Matt Maybeno
Mohammed Rafii-El-Idrissi Benhnia
Danielle Becker
Xiangzhi Meng
Yan Xiang
Shane Crotty
Bjoern Peters
Dirk M Zajonc
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| method: |
x-ray crystallography
|
| name: |
Structural and biochemical characterization of the vaccinia virus envelope protein D8 and its recognition by the antibody LA5.
|
| description: |
strain Acam2000
The epitope of L85 Fab on the VACV envelope D8 protein was determined from the crystal structure of the Fab bound to the D8 (1-261) ectodomain, solved by molecular replacement. Construct D8 (1-261) exists predominantly as a monomer. There are two complexes in the asymmetric unit.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
