Development of a novel immunoassay for the measurement of type II collagen neoepitope generated by collagenase cleavage.

Title:

Development of a novel immunoassay for the measurement of type II collagen neoepitope generated by collagenase cleavage.

identifier:	1945914
description:	epitope description:GPPGPQG + HYL(P3) antigen name:Collagen alpha-1(II) chain host organism:Mus musculus A/J antibody name:20A10
aggregation:	instance of dataset
availability:	available
primaryPublications:	22507082

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Tatsuya Takahashi Shoichi Naito Junji Onoda Akira Yamauchi Etsuo Nakamura Junji Kishino Taeko Kawai Satoko Matsukawa Tomoko Toyosaki-Maeda Miki Tanimura Naoshi Fukui Yoshito Numata Shoji Yamane

method:	antigen inhibition

name:	Development of a novel immunoassay for the measurement of type II collagen neoepitope generated by collagenase cleavage.
description:	The peptide inhibited binding of the epitope-specific mAb to the biotinylated peptide. The same peptide which was hydroxylated at position P15 also inhibited binding. Direct binding assay was also positive.

name:	iedb
homePage:	http://www.iedb.org

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