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identifier: 1952715
description:
epitope description:beta-D-mannopyranosyl-(1->2)-beta-D-mannopyranosyl-(1->2)-beta-D-mannopyranosyl group
antigen name:(1->2)-beta-D-mannan
host organism:Mus musculus BALB/cByJ
antibody name:C3.1
aggregation:
instance of dataset
availability:
available
primaryPublications: 22493450
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1024406
landingPage: http://www.iedb.org/assay/1952715
type:
Literature
publicationVenue:
J Biol Chem
dates:
2012
study type: b cell assays
subject species: Candida albicans
fullName:
Margaret A Johnson
Jonathan Cartmell
Nina E Weisser
Robert J Woods
David R Bundle
method:
surface plasmon resonance (SPR)
name:
Molecular recognition of Candida albicans (1->2)-beta-mannan oligosaccharides by a protective monoclonal antibody reveals the immunodominance of internal saccharide residues.
description:
Affinity of the scFv to the epitope was determined by surface plasmon resonance (SPR). Similar results were obtained with the complete antibody in inhibition ELISA (IC50 = 25 µM).

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