Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1955430 |
| description: |
epitope description:P49, S50, C52, L53, M54, D55, R56, H57, D58, Q63, E165, V166, A169, E170, R173, L177
antigen name:Interferon alpha-1/13
host organism:Homo sapiens
antibody name:AIFNalpha1bScFv01
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
22307521 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1025004 |
| landingPage: |
http://www.iedb.org/assay/1955430 |
| type: |
Literature
|
| publicationVenue: |
J Mol Med (Berl)
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Songying Ouyang
Bin Gong
Jin-Zhi Li
Li-Xia Zhao
Wei Wu
Fu-Shun Zhang
Lina Sun
Shu-Jun Wang
Meng Pan
Chuan Li
Wenguang Liang
Neil Shaw
Jie Zheng
Guo-Ping Zhao
Ying Wang
Zhi-Jie Liu
Mifang Liang
|
| method: |
x-ray crystallography
|
| name: |
Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus.
|
| description: |
Epitope residues are calculated from [PDB: 3UX9] as the antigen residues at 4Å
atomic distance from the antibody.
The epitope of AIFNalpha1bScFv01 on IFNalpha1b was determined from the crystal structure of the complex, solved by molecular replacement.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
