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identifier: 1956149
description:
epitope description:QLINTNGSWHIN
antigen name:Genome polyprotein
host organism:Mus musculus BALB/c
antibody name:AP33
aggregation:
instance of dataset
availability:
available
primaryPublications: 22973046
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1025105
landingPage: http://www.iedb.org/assay/1956149
type:
Literature
publicationVenue:
J Virol
dates:
2012
study type: b cell assays
subject species: Hepatitis C virus
fullName:
Leopold Kong
Erick Giang
Travis Nieusma
Justin B Robbins
Marc C Deller
Robyn L Stanfield
Ian A Wilson
Mansun Law
method:
biological activity
name:
Structure of hepatitis C virus envelope glycoprotein E2 antigenic site 412 to 423 in complex with antibody AP33.
description:
The epitope-specific mAb AP33 neutralized HCV pseudotype virus particles (HCVpp) displaying the genotype 1a or 1b E1E2. Mutation of residue N415 to K, Q or E (position 4 in the epitope) abolished recognition by AP33.

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