| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1025105 |
| landingPage: |
http://www.iedb.org/assay/1956149 |
| type: |
Literature
|
| publicationVenue: |
J Virol
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Hepatitis C virus |
| fullName: |
Leopold Kong
Erick Giang
Travis Nieusma
Justin B Robbins
Marc C Deller
Robyn L Stanfield
Ian A Wilson
Mansun Law
|
| method: |
biological activity
|
| name: |
Structure of hepatitis C virus envelope glycoprotein E2 antigenic site 412 to 423 in complex with antibody AP33.
|
| description: |
The epitope-specific mAb AP33 neutralized HCV pseudotype virus particles (HCVpp) displaying the genotype 1a or 1b E1E2. Mutation of residue N415 to K, Q or E (position 4 in the epitope) abolished recognition by AP33.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |