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Title: Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization.
identifier: 1953146
description:
epitope description:EVDGQQLAQSQAICRYLAKT
antigen name:Glutathione S-transferase 2
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 22541242
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1024481
landingPage: http://www.iedb.org/assay/1953146
type:
Literature
publicationVenue:
J Allergy Clin Immunol
dates:
2012
study type: b cell assays
subject species: Heligmosomoides polygyrus
fullName:
Helton C Santiago
Elyse LeeVan
Sasisekhar Bennuru
Flavia Ribeiro-Gomes
Ellen Mueller
Mark Wilson
Thomas Wynn
David Garboczi
Joseph Urban
Edward Mitre
Thomas B Nutman
method:
antigen inhibition
name:
Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization.
description:
The epitope inhibited IgE binding to Bla g 5 or WbGST, using sera from filaria-infected patients positive for anti-Bla g 5 and anti-WbGST antibodies.

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