Guillain-Barré syndrome with IgM antibody to the ganglioside GalNAc-GD1a. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Guillain-Barré syndrome with IgM antibody to the ganglioside GalNAc-GD1a.

Dataset

identifier:	1953463
description:	epitope description:beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	11164910

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/983
landingPage:	http://www.iedb.org/assay/1953463

Publication

type:	Literature
publicationVenue:	J Neuroimmunol
dates:	2001

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	K Kaida S Kusunoki K Kamakura K Motoyoshi I Kanazawa

Data Type

method:	ELISA

Study

name:	Guillain-Barré syndrome with IgM antibody to the ganglioside GalNAc-GD1a.
description:	In patients with Guillian-Barre syndrome subsequent to gastrointestinal (mostly C. jejuni) infection with positive IgM and negative IgG to GalNAc-GD1a, IgM class antibodies to GM2 ganglioside were detected. In a preabsorption experiment, the GM2 ganglioside was able to absorb 21% of the reactivity to GalNAc-GD1a, confirming the cross-reactivity among the two gangliosides is detected but to a small extent in this group.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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