Identification of the IgE-binding epitope in omega-5 gliadin, a major allergen in wheat-dependent exercise-induced anaphylaxis.

Title:

Identification of the IgE-binding epitope in omega-5 gliadin, a major allergen in wheat-dependent exercise-induced anaphylaxis.

identifier:	1953732
description:	epitope description:QQFPQQQ antigen name:Other Triticum aestivum (Canadian hard winter wheat) protein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	14699123

study type:	b cell assays
subject species:	Triticum aestivum

fullName:	Hiroaki Matsuo Eishin Morita Arthur Sydney Tatham Kenichi Morimoto Tatsuya Horikawa Hiroyuki Osuna Zenro Ikezawa Sakae Kaneko Kunie Kohno Satoshi Dekio

method:	western blot

name:	Identification of the IgE-binding epitope in omega-5 gliadin, a major allergen in wheat-dependent exercise-induced anaphylaxis.
description:	The minimal epitope sequence was deduced through study of overlapping 10-mer peptides. Single alanine substitutions showed that positions Gln1, Pro4, Gln5, Gln6 and Gln7 were critical amino acids for IgE binding.

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.