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Title: Galalpha1-4Galbeta1-3GalNAc is the dominant epitope of Em2 antigen, the mucin-type glycoprotein from Echinococcus multilocularis.
identifier: 1953861
description:
epitope description:alpha-D-Galp-(1->4)-beta-D-Galp-(1->3)-alpha-D-GalpNAc
antigen name:O-glycoprotein
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 22461008
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1024954
landingPage: http://www.iedb.org/assay/1953861
type:
Literature
publicationVenue:
Parasitol Res
dates:
2012
study type: b cell assays
subject species: Echinococcus multilocularis
fullName:
Kimiaki Yamano
Akihiko Koizumi
Tadahiro Takeda
Fumiyuki Kiuchi
Noriyasu Hada
method:
ELISA
name:
Galalpha1-4Galbeta1-3GalNAc is the dominant epitope of Em2 antigen, the mucin-type glycoprotein from Echinococcus multilocularis.
description:
The epitope is part of the O-glycan found in the mucin-type Em2 glycoprotein antigen from E. multiocularis.
The biotin-spacer-oligosaccharide was used as antigen linked to streptavidin coated ELISA plates. When preabsortion experiments were performed with the terminal disaccharide alpha-D-Galp-(1->4)-beta-D-Galp, the number of positive samples remained unchanged.

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