Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.

Dataset

identifier:	1954676
description:	epitope description:QLINTNGSWHIN antigen name:Genome polyprotein host organism:Mus musculus HuMAb (Medarex)
aggregation:	instance of dataset
availability:	available
primaryPublications:	22952447

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025098
landingPage:	http://www.iedb.org/assay/1954676

Publication

type:	Literature
publicationVenue:	PLoS Pathog
dates:	2012

Dimension

study type:	b cell assays
subject species:	Hepatitis C virus (isolate H77)

Person

fullName:	Trevor J Morin Teresa J Broering Brett A Leav Barbra M Blair Kirk J Rowley Elisabeth N Boucher Yang Wang Peter S Cheslock Michael Knauber David B Olsen Steve W Ludmerer Gyongyi Szabo Robert W Finberg Robert H Purcell Robert E Lanford Donna M Ambrosino Deborah C Molrine Gregory J Babcock

Data Type

method:	in vivo assay

Study

name:	Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.
description:	The epitope-specific mAb was shown to prevent HCV infection and was able to treat chronically infected chimps.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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