Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1954878 |
| description: |
epitope description:A: H44, Q46, D47, I48, S304, M305, P306; B: V364, D365, G366, W367, A382, K384, T387, Q388, I391, D392, V394, T395, V398, I402
antigen name:Hemagglutinin
host organism:Homo sapiens
antibody name:CR9114
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
22878502 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1025035 |
| landingPage: |
http://www.iedb.org/assay/1954878 |
| type: |
Literature
|
| publicationVenue: |
Science
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Influenza A virus (A/Viet Nam/1203/2004(H5N1)) |
| fullName: |
Cyrille Dreyfus
Nick S Laursen
Ted Kwaks
David Zuijdgeest
Reza Khayat
Damian C Ekiert
Jeong Hyun Lee
Zoltan Metlagel
Miriam V Bujny
Mandy Jongeneelen
Remko van der Vlugt
Mohammed Lamrani
Hans J W M Korse
Eric Geelen
Ö
zcan Sahin
Martijn Sieuwerts
Just P J Brakenhoff
Ronald Vogels
Olive T W Li
Leo L M Poon
Malik Peiris
Wouter Koudstaal
Andrew B Ward
Ian A Wilson
Jaap Goudsmit
Robert H E Friesen
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Highly conserved protective epitopes on influenza B viruses.
|
| description: |
The epitope-reactive mAb Fab CR9114 bound to a wide range of influenza A and B hemagglutinins. Hemagglutinins from influenza B virus exhibited 2:1 binding with CR9114, with similar affinities for the two binding processes (KD1 = 78 nM and KD2 = 170 nM).
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
