New insights into the antigenic structure of the glycoprotein E(rns) of classical swine fever virus by epitope mapping.

Title:

New insights into the antigenic structure of the glycoprotein E(rns) of classical swine fever virus by epitope mapping.

identifier:	1961252
description:	epitope description:LRGISRSLHGIWPEK antigen name:Genome polyprotein host organism:Mus musculus antibody name:HC/TC 57, 61, 66 and 69
aggregation:	instance of dataset
availability:	available
primaryPublications:	22868042

study type:	b cell assays
subject species:	Classical swine fever virus - Alfort/187

fullName:	Denise Meyer Andrea Aebischer Matthias Mü ller Beatrice Grummer Irene Greiser-Wilke Volker Moennig Martin A Hofmann

method:	western blot

name:	New insights into the antigenic structure of the glycoprotein E(rns) of classical swine fever virus by epitope mapping.
description:	The epitope sequence was derived from the author provided accession X87939 (GI:871251). To determine epitope motifs within the antibody binding site (aa55-110) defined by reactivity to chimeric proteins, as well as mutation analysis, an overlapping peptide library representing the entire CSFV E protein was used to screen mAbs. Positive reactivity of adjacent peptides showed GIWPEKICK as the motif.

name:	iedb
homePage:	http://www.iedb.org

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