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identifier: 1958955
description:
epitope description:beta-D-QuiN4Fm-(1->4)-alpha-D-GalNAcAN-(1->4)-alpha-D-GalNAcAN-(1->3)-beta-D-QuiNAc-(1->4)-[alpha-D-GalN-(1->2)]-[alpha-D-Glc-(1->3)]-beta-D-Man-(1->4)-[beta-D-Glc-(1->2)]-alpha-D-Man-(1->5)-alpha-Kdo
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
antibody name:Ab52
aggregation:
instance of dataset
availability:
available
primaryPublications: 22486311
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1024410
landingPage: http://www.iedb.org/assay/1958955
type:
Literature
publicationVenue:
Immunology
dates:
2012
study type: b cell assays
subject species: Francisella tularensis subsp. holarctica LVS
fullName:
Zhaohua Lu
Guillermo Madico
Marly I Roche
Qi Wang
Julia H Hui
Hillary M Perkins
Joseph Zaia
Catherine E Costello
Jacqueline Sharon
method:
antigen inhibition (~ IC50)
name:
Protective B-cell epitopes of Francisella tularensis O-polysaccharide in a mouse model of respiratory tularaemia.
description:
The epitope structure is composed of the core and two repeats of the O-Ag region of F. tularensis holartica LPS. It can be found in Gunn and Ernst Ann N Y Acad Sci. 2007 1105:202 [PMID:17395723].
The epitope is the fragment most effective at inhibiting the binding of the mAb to solid phase-bound OAg-core of F. tularensis LPS.

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