| identifier: | 1958955 |
| description: |
epitope description:beta-D-QuiN4Fm-(1->4)-alpha-D-GalNAcAN-(1->4)-alpha-D-GalNAcAN-(1->3)-beta-D-QuiNAc-(1->4)-[alpha-D-GalN-(1->2)]-[alpha-D-Glc-(1->3)]-beta-D-Man-(1->4)-[beta-D-Glc-(1->2)]-alpha-D-Man-(1->5)-alpha-Kdo
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
antibody name:Ab52
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
22486311 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1024410 |
| landingPage: |
http://www.iedb.org/assay/1958955 |
| type: |
Literature
|
| publicationVenue: |
Immunology
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Francisella tularensis subsp. holarctica LVS |
| fullName: |
Zhaohua Lu
Guillermo Madico
Marly I Roche
Qi Wang
Julia H Hui
Hillary M Perkins
Joseph Zaia
Catherine E Costello
Jacqueline Sharon
|
| method: |
antigen inhibition (~ IC50)
|
| name: |
Protective B-cell epitopes of Francisella tularensis O-polysaccharide in a mouse model of respiratory tularaemia.
|
| description: |
The epitope structure is composed of the core and two repeats of the O-Ag region of F. tularensis holartica LPS. It can be found in Gunn and Ernst Ann N Y Acad Sci. 2007 1105:202 [PMID:17395723].
The epitope is the fragment most effective at inhibiting the binding of the mAb to solid phase-bound OAg-core of F. tularensis LPS.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |