Immunization with a combination of 2 peptides derived from the C5a receptor significantly reduces early atherosclerotic lesion in Ldlr(tm1Her) Apob(tm2Sgy) J mice.

Title:

Immunization with a combination of 2 peptides derived from the C5a receptor significantly reduces early atherosclerotic lesion in Ldlr(tm1Her) Apob(tm2Sgy) J mice.

Dataset

identifier:	1959586
description:	epitope description:MDSFNYTTPDYGHYDDKDTLD antigen name:C5a anaphylatoxin chemotactic receptor 1 host organism:Mus musculus C57BL/6
aggregation:	instance of dataset
availability:	available
primaryPublications:	22837469

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025088
landingPage:	http://www.iedb.org/assay/1959586

Publication

type:	Literature
publicationVenue:	Arterioscler Thromb Vasc Biol
dates:	2012

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Xinjie Lu Min Xia Valeria Endresz Ildiko Faludi Lakshmi Mundkur Eva Gonczol Daxin Chen Vijay V Kakkar

Data Type

method:	ELISA

Study

name:	Immunization with a combination of 2 peptides derived from the C5a receptor significantly reduces early atherosclerotic lesion in Ldlr(tm1Her) Apob(tm2Sgy) J mice.
description:	The epitope sequence is from the cited reference: Hagemann et al. (2006) J Biol Chem 281: 36783-36792 [PMID: 17023413]. The antigen peptide was synthesized with an N-terminal cysteine residue for attachment to the ELISA plate.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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