| identifier: | 1959831 |
| description: |
epitope description:Y115, T148, G151, G152, S153, S154, W170, Y172, K173, S174, G175, S176, K206, E207, N210, L211, V213, L243
antigen name:Hemagglutinin
host organism:Mus musculus BALB/c
antibody name:S139/1
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
23027945 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1025198 |
| landingPage: |
http://www.iedb.org/assay/1959831 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Influenza A virus (A/Victoria/3/1975(H3N2)) |
| fullName: |
Peter S Lee
Reiko Yoshida
Damian C Ekiert
Naoki Sakai
Yasuhiko Suzuki
Ayato Takada
Ian A Wilson
|
| method: |
bio-layer interferometry assay
|
| name: |
Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity.
|
| description: |
The epitope specific mAb S139/1 bound to hemagglutinin from influenza A virus of multiple subtypes, as determined bi bio-layer interferometry. S139/1 IgG (KD = 250 nM) bound weakly but with higher affinity than the Fab (KD > 1000 nM).
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |