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identifier: 1959831
description:
epitope description:Y115, T148, G151, G152, S153, S154, W170, Y172, K173, S174, G175, S176, K206, E207, N210, L211, V213, L243
antigen name:Hemagglutinin
host organism:Mus musculus BALB/c
antibody name:S139/1
aggregation:
instance of dataset
availability:
available
primaryPublications: 23027945
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1025198
landingPage: http://www.iedb.org/assay/1959831
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2012
study type: b cell assays
subject species: Influenza A virus (A/Victoria/3/1975(H3N2))
fullName:
Peter S Lee
Reiko Yoshida
Damian C Ekiert
Naoki Sakai
Yasuhiko Suzuki
Ayato Takada
Ian A Wilson
method:
bio-layer interferometry assay
name:
Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity.
description:
The epitope specific mAb S139/1 bound to hemagglutinin from influenza A virus of multiple subtypes, as determined bi bio-layer interferometry. S139/1 IgG (KD = 250 nM) bound weakly but with higher affinity than the Fab (KD > 1000 nM).

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