Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1959747 |
| description: |
epitope description:L32, F33, W36, K64, Y65, Y84, P86, W87, R108, P110, R111, G112, Q113, W115, R116, A118, Q122
antigen name:Glucagon receptor
host organism:Mus musculus Xenomouse
antibody name:mAb1
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
22908259 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1025185 |
| landingPage: |
http://www.iedb.org/assay/1959747 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Christopher M Koth
Jeremy M Murray
Susmith Mukund
Azadeh Madjidi
Alexandra Minn
Holly J Clarke
Terence Wong
Vicki Chiang
Elizabeth Luis
Alberto Estevez
Jesus Rondon
Yingnan Zhang
Isidro Hö
tzel
Bernard B Allan
|
| method: |
ELISA
|
| name: |
Molecular basis for negative regulation of the glucagon receptor.
|
| description: |
The epitope specific mAb1 bound to cells expressing the WT glucagon receptor (GCGR) or chimeras of GCGR with mutations in the extracellular loops. MAb1 also bound to detergent-solubilized GCGR.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
