Immunogenetic mechanisms driving norovirus GII.4 antigenic variation. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Immunogenetic mechanisms driving norovirus GII.4 antigenic variation.

Dataset

identifier:	1959853
description:	epitope description:STT antigen name:Capsid protein VP1 host organism:Homo sapiens antibody name:NVB97
aggregation:	instance of dataset
availability:	available
primaryPublications:	22615565

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1024204
landingPage:	http://www.iedb.org/assay/1959853

Publication

type:	Literature
publicationVenue:	PLoS Pathog
dates:	2012

Dimension

study type:	b cell assays
subject species:	Norovirus Hu/GII.4/Minerva/2006/USA

Person

fullName:	Lisa C Lindesmith Martina Beltramello Eric F Donaldson Davide Corti Jesica Swanstrom Kari Debbink Antonio Lanzavecchia Ralph S Baric

Data Type

method:	biological activity

Study

name:	Immunogenetic mechanisms driving norovirus GII.4 antigenic variation.
description:	The epitope-specific mAb blocks the interaction between the Novovirus VLP and Pig Gastric Mucin Type III (PGM). The mAb was also shown to block blockade VLP-synthetic biotinylated HBGA (Bi-HBGA) interaction.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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