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Title: Epitope spreading of the anti-CYP2D6 antibody response in patients with autoimmune hepatitis and in the CYP2D6 mouse model.
identifier: 1959981
description:
epitope description:RMTWDPAQPPRD
antigen name:Cytochrome P450 2D6
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 21795021
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1025221
landingPage: http://www.iedb.org/assay/1959981
type:
Literature
publicationVenue:
J Autoimmun
dates:
2011
study type: b cell assays
subject species: Homo sapiens
fullName:
Edith Hintermann
Martin Holdener
Monika Bayer
Stephanie Loges
Josef M Pfeilschifter
Claude Granier
Michael P Manns
Urs Christen
method:
ELISA
name:
Epitope spreading of the anti-CYP2D6 antibody response in patients with autoimmune hepatitis and in the CYP2D6 mouse model.
description:
The epitope sequence was deduced by study of overlapping peptides.
The epotope was among the first epitopes recognized by patient sera after diagnosis of autoimmune hepatitis. The epitope recognition was stable over the course of the disease.

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