Identification of a major linear C1q epitope allows detection of systemic lupus erythematosus anti-C1q antibodies by a specific peptide-based enzyme-linked immunosorbent assay.

Title:

Identification of a major linear C1q epitope allows detection of systemic lupus erythematosus anti-C1q antibodies by a specific peptide-based enzyme-linked immunosorbent assay.

Dataset

identifier:	1961704
description:	epitope description:PGKVGPKGPMGPK antigen name:Complement C1q subcomponent subunit B host organism:Homo sapiens antibody name:clones A4 and A14
aggregation:	instance of dataset
availability:	available
primaryPublications:	22740328

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025233
landingPage:	http://www.iedb.org/assay/1961704

Publication

type:	Literature
publicationVenue:	Arthritis Rheum
dates:	2012

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Dominique Vanhecke Lubka T Roumenina Hui Wan Michael Osthoff Monica Schaller Marten Trendelenburg

Data Type

method:	microarray

Study

name:	Identification of a major linear C1q epitope allows detection of systemic lupus erythematosus anti-C1q antibodies by a specific peptide-based enzyme-linked immunosorbent assay.
description:	Microarray-based peptide scan of overlapping peptides was used to identify the epitope. The epitope-specific Fab recognized the epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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