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Title: Mapping of epitopes relevant for induction of acrosome reaction on human zona pellucida glycoprotein-4 using monoclonal antibodies.
identifier: 1962523
description:
epitope description:ENELV
antigen name:Zona pellucida sperm-binding protein 4
host organism:Mus musculus BALB/c
antibody name:MA-1662
aggregation:
instance of dataset
availability:
available
primaryPublications: 22860757
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1025237
landingPage: http://www.iedb.org/assay/1962523
type:
Literature
publicationVenue:
Am J Reprod Immunol
dates:
2012
study type: b cell assays
subject species: Homo sapiens
fullName:
Wan-Xiang Xu
Beena Bhandari
Ya-Ping He
Hai-Ping Tang
Sanchita Chaudhary
Pankaj Talwar
Satish K Gupta
Jian Wang
method:
biological activity
name:
Mapping of epitopes relevant for induction of acrosome reaction on human zona pellucida glycoprotein-4 using monoclonal antibodies.
description:
The epitope was deduced.
Preincubation of ZP4 with the epitope-specific mAb MA-1662 significantly decreased the acrosome reaction induced by incubation of ZP4 with capacitated human sperm.

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