Characterization of conformation-dependent prion protein epitopes. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Characterization of conformation-dependent prion protein epitopes.

Dataset

identifier:	1963147
description:	epitope description:DYEDRYYRE antigen name:Major prion protein host organism:Mus musculus PrP null antibody name:6H4
aggregation:	instance of dataset
availability:	available
primaryPublications:	22948149

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025257
landingPage:	http://www.iedb.org/assay/1963147

Publication

type:	Literature
publicationVenue:	J Biol Chem
dates:	2012

Dimension

study type:	b cell assays
subject species:	Cervus canadensis nelsoni

Person

fullName:	Hae-Eun Kang Chu Chun Weng Eri Saijo Vicki Saylor Jifeng Bian Sehun Kim Laylaa Ramos Rachel Angers Katie Langenfeld Vadim Khaychuk Carla Calvi Jason Bartz Nora Hunter Glenn C Telling

Data Type

method:	western blot

Study

name:	Characterization of conformation-dependent prion protein epitopes.
description:	The reference positions refer to those relative to the mouse PrP protein. The mouse sequence for this epitope is DWEDRYYRE, with a Y to W substitution at position 2. The epitope-specific mAb reacted with Deer PrP, which harbors the epitope sequence, in Western blot. The deer PrP tested is shared (at least) by white-tailed deer (Odocoileus virginianus) and mule deer (Odocoileus hemionus).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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