Amino acid residue-specific neutralization and nonneutralization of hepatitis C virus by monoclonal antibodies to the E2 protein.

Title:

Amino acid residue-specific neutralization and nonneutralization of hepatitis C virus by monoclonal antibodies to the E2 protein.

identifier:	1963447
description:	epitope description:NTGWLAGLFYQHK antigen name:Genome polyprotein host organism:Mus musculus BALB/c antibody name:MAb #41
aggregation:	instance of dataset
availability:	available
primaryPublications:	22973024

study type:	b cell assays
subject species:	Hepatitis C virus (isolate H77)

fullName:	Hongying Duan Alla Kachko Lilin Zhong Evi Struble Shivani Pandey Hailing Yan Christine Harman Maria Luisa Virata-Theimer Lu Deng Zhong Zhao Marian Major Stephen Feinstone Pei Zhang

method:	biological activity

name:	Amino acid residue-specific neutralization and nonneutralization of hepatitis C virus by monoclonal antibodies to the E2 protein.
description:	The epitope-specific mAb abitlity to neutralize the infectivity on Huh 7.5 cells of an HCV genotype 1a/2a chimera virus was inhibited by pre-absorption of the mAb with peptide B containing the epitope.

name:	iedb
homePage:	http://www.iedb.org

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