Structural basis for the dual recognition of helical cytokines IL-34 and CSF-1 by CSF-1R. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Structural basis for the dual recognition of helical cytokines IL-34 and CSF-1 by CSF-1R.

Dataset

identifier:	1969122
description:	epitope description:A: Y47, K55, N61, K63, R73, I74, L158, R160, K162, D166, N167, R170; B: P154, N155 antigen name:Interleukin-34 host organism:Homo sapiens antibody name:Ab2
aggregation:	instance of dataset
availability:	available
primaryPublications:	22483114

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025007
landingPage:	http://www.iedb.org/assay/1969122

Publication

type:	Literature
publicationVenue:	Structure
dates:	2012

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Xiaolei Ma Wei Yu Lin Yongmei Chen Scott Stawicki Kiran Mukhyala Yan Wu Flavius Martin J Fernando Bazan Melissa A Starovasnik

Data Type

method:	surface plasmon resonance (SPR)

Study

name:	Structural basis for the dual recognition of helical cytokines IL-34 and CSF-1 by CSF-1R.
description:	The binding kinetics of epitope-specific nonblocking antibody Ab2 for human IL-34 was determined by Octet measurement.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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