An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition.

Title:

An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition.

identifier:	1966752
description:	epitope description:EIVYKSPVVSGDTSPRHL + PHOS(S6, S14) antigen name:Microtubule-associated protein tau host organism:Gallus gallus antibody name:anti-pS396/pS404_1
aggregation:	instance of dataset
availability:	available
primaryPublications:	23148212

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Heather H Shih Chao Tu Wei Cao Anne Klein Renee Ramsey Brian J Fennell Matthew Lambert Deirdre Ní Shú illeabhá in Bé né dicte Autin Eugenia Kouranova Sri Laxmanan Steven Braithwaite Leeying Wu Mostafa Ait-Zahra Anthony J Milici Jo Ann Dumin Edward R LaVallie Maya Arai Christopher Corcoran Janet E Paulsen Davinder Gill Orla Cunningham Joel Bard Lydia Mosyak William J J Finlay

method:	surface plasmon resonance (SPR)

name:	An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition.
description:	The binding affinity of anti-phospho-tau mAb (pS396/pS404_1) for the phosphoepitope was determined by surface plasmon resonance. The epitope was synthesized with a C-terminal Cys residue.

name:	iedb
homePage:	http://www.iedb.org

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