Fully human broadly neutralizing monoclonal antibodies against influenza A viruses generated from the memory B cells of a 2009 pandemic H1N1 influenza vaccine recipient.

Title:

Fully human broadly neutralizing monoclonal antibodies against influenza A viruses generated from the memory B cells of a 2009 pandemic H1N1 influenza vaccine recipient.

Dataset

identifier:	1966833
description:	epitope description:FIEGGWTGMVDGWYGYHH antigen name:Hemagglutinin host organism:Homo sapiens antibody name:1F2, 1F4, 1E1
aggregation:	instance of dataset
availability:	available
primaryPublications:	23084424

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025399
landingPage:	http://www.iedb.org/assay/1966833

Publication

type:	Literature
publicationVenue:	Virology
dates:	2013

Dimension

study type:	b cell assays
subject species:	Influenza A virus (A/California/04/2009(H1N1))

Person

fullName:	Weibin Hu Aizhong Chen Yi Miao Shengli Xia Zhiyang Ling Ke Xu Tongyan Wang Ying Xu Jun Cui Hongqiang Wu Guiyu Hu Lin Tian Lingling Wang Yuelong Shu Xiaowei Ma Bianli Xu Jin Zhang Xiaojun Lin Chao Bian Bing Sun

Data Type

method:	ELISA

Study

name:	Fully human broadly neutralizing monoclonal antibodies against influenza A viruses generated from the memory B cells of a 2009 pandemic H1N1 influenza vaccine recipient.
description:	Sequence alignment shows that some amino acid residues in the epitope are conserved among viruses of different subtypes. Three epitope-specific mAbs reacted with virus lysate from H1N1 strain A/California/7/2009 (which contains the epitope sequence).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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