Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1967620 |
| description: |
epitope description:alpha-D-GlcN-(1->2)-alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-L-alpha-D-Hep4P-(1->3)-L-alpha-D-Hep4P-(1->5)-[alpha-D-Kdo-(2->4)]-alpha-D-Kdo-(2->6)-beta-D-GlcN4P-(1->6)-alpha-D-Glc1P
antigen name:lipopolysaccharide
host organism:Mus musculus NZB
antibody name:WN1 225-5
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
23184990 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1025383 |
| landingPage: |
http://www.iedb.org/assay/1967620 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Escherichia coli F576 |
| fullName: |
Kathryn Gomery
Sven Mü
ller-Loennies
Cory L Brooks
Lore Brade
Paul Kosma
Franco Di Padova
Helmut Brade
Stephen V Evans
|
| method: |
antigen inhibition (~ IC50)
|
| name: |
Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS.
|
| description: |
The E.coli J-5 octasaccharide-P4 inhibited the binding of epitope-specific WN1 222-5 mAb to the epitope, dodecasaccharide-P4, by ELISA inhibition assay. Octasaccharide-P4 was the smallest structure capable of strong binding to mAb WN1 222-5 in direct ELISA.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
