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Title: Molecular basis of antibody mediated immunity against Ehrlichia chaffeensis involves species-specific linear epitopes in tandem repeat proteins.
identifier: 1969704
description:
epitope description:SKVEQEETNPEVLIKDLQDVAS
antigen name:120 kDa immunodominant surface protein
host organism:Mus musculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 22658957
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1025124
landingPage: http://www.iedb.org/assay/1969704
type:
Literature
publicationVenue:
Microbes Infect
dates:
2012
study type: b cell assays
subject species: Ehrlichia chaffeensis
fullName:
Jeeba A Kuriakose
Xiaofeng Zhang
Tian Luo
Jere W McBride
method:
in vivo assay
name:
Molecular basis of antibody mediated immunity against Ehrlichia chaffeensis involves species-specific linear epitopes in tandem repeat proteins.
description:
A significant reduction in ehrlichial copy number was observed when epitope-specific antisera were administered to SCID mice during the course of the infection. Antibody treated mice had significantly lower spleen weights than the controls.

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