Targeted delivery of interferon-alpha to hepatitis B virus-infected cells using T-cell receptor-like antibodies.

Title:

Targeted delivery of interferon-alpha to hepatitis B virus-infected cells using T-cell receptor-like antibodies.

identifier:	1970221
description:	epitope description:FLLTRILTI antigen name:Large envelope protein host organism:Mus musculus BALB/c antibody name:sTCR-L
aggregation:	instance of dataset
availability:	available
primaryPublications:	22684948

study type:	b cell assays
subject species:	Hepatitis B virus

fullName:	Changhua Ji Konduru S R Sastry Georg Tiefenthaler Jennifer Cano Tenny Tang Zi Zong Ho Denise Teoh Sandhya Bohini Antony Chen Surya Sankuratri Paul A Macary Patrick Kennedy Han Ma Stefan Ries Klaus Klumpp Erhard Kopetzki Antonio Bertoletti

method:	flow cytometry

name:	Targeted delivery of interferon-alpha to hepatitis B virus-infected cells using T-cell receptor-like antibodies.
description:	The sTCR-like antibody specific for the epitope/HLA-A02:01 complex recognized T2 cells expressing HLA-A02:01 and pulsed with the epitope. The sTCR-L mAb also recognized HBV-B cells expressing HLA-A02 allotypes, A02:02 or A*02:11, and pulsed with the epitope. The sTCR-L mAb did not recognize cells pulsed with the analogous peptide FLLTKILTI from HBV genotypes B, E and F.

name:	iedb
homePage:	http://www.iedb.org

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