Low levels of IgM antibodies to oxidized cardiolipin increase and high levels decrease risk of cardiovascular disease among 60-year olds: a prospective study.

Title:

Low levels of IgM antibodies to oxidized cardiolipin increase and high levels decrease risk of cardiovascular disease among 60-year olds: a prospective study.

Dataset

identifier:	1970260
description:	epitope description:oxidised cardiolipin host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	23294904

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025482
landingPage:	http://www.iedb.org/assay/1970260

Publication

type:	Literature
publicationVenue:	BMC Cardiovasc Disord
dates:	2013

Dimension

study type:	b cell assays
subject species:	Bos taurus

Person

fullName:	Jun Su Xiang Hua Max Vikströ m Karin Leander Bruna Gigante Mai-Lis Hellenius Ulf de Faire Johan Frostegå rd

Data Type

method:	antigen inhibition

Study

name:	Low levels of IgM antibodies to oxidized cardiolipin increase and high levels decrease risk of cardiovascular disease among 60-year olds: a prospective study.
description:	The epitope inhibited the binding of sera to itself, to beta2GP1, but not to PC-BSA. Anti-epitope IgM was lower among CVD cases than controls (84.16 U/ml compared to 96.90 U/ml for men, and 99.06 U/ml compared to 96.75 for women). High levels of anti-epitope IgM were associated with decreased risk of cardiovascular diseases.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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