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Title: A sequence in subdomain 2 of DBL1alpha of Plasmodium falciparum erythrocyte membrane protein 1 induces strain transcending antibodies.
identifier: 1970894
description:
epitope description:REYWWALNRKEVWKA
antigen name:Erythrocyte membrane protein 1, PfEMP1 (UniProt:Q8I639)
host organism:Oryctolagus cuniculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 23335956
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1025501
landingPage: http://www.iedb.org/assay/1970894
type:
Literature
publicationVenue:
PLoS One
dates:
2013
study type: b cell assays
subject species: Plasmodium falciparum isolate UAS22
fullName:
Karin Blomqvist
Letusa Albrecht
Maria del Pilar Quintana
Davide Angeletti
Nicolas Joannin
Arnaud Chê
ne
Kirsten Moll
Mats Wahlgren
method:
ELISA
name:
A sequence in subdomain 2 of DBL1alpha of Plasmodium falciparum erythrocyte membrane protein 1 induces strain transcending antibodies.
description:
The epitope sequence was derived from a clinical isolate of P. falciparum UAS22 from subjects in Uganda.
The epitope was deduced using overlapping 15mers. Alanine replacement revealed positions 3-13 (Y, W, W, L, N, R, K, E, V, W) to be critical for binding.

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