Characterisation and haemagglutinin gene epitope mapping of a variant strain of H5N1 subtype avian influenza virus.

Title:

Characterisation and haemagglutinin gene epitope mapping of a variant strain of H5N1 subtype avian influenza virus.

identifier:	1970407
description:	epitope description:L145, E155, N156 antigen name:Hemagglutinin host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	23265247

study type:	b cell assays
subject species:	Influenza A virus (A/chicken/Huadong/4/2008(H5N1))

fullName:	Yanfang Li Xiaojian Zhang Quangang Xu Qiang Fu Yinbiao Zhu Sujuan Chen Daxin Peng Xiufan Liu

method:	biological activity

name:	Characterisation and haemagglutinin gene epitope mapping of a variant strain of H5N1 subtype avian influenza virus.
description:	The reactivity to the WT virus was significantly affected by mutation at the epitope residues, where L129 (L145) was deleted and E139 and N140 (E155 and N156) were mutated to G and K, respectively, to generate mutations corresponding to the residues present in the A/Chicken/Shanxi/2/2006 strain, which is the source of the commercial Re-4 vaccine.

name:	iedb
homePage:	http://www.iedb.org

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