The epitope of monoclonal antibodies blocking erythrocyte invasion by Plasmodium falciparum map to the dimerization and receptor glycan binding sites of EBA-175.

Title:

The epitope of monoclonal antibodies blocking erythrocyte invasion by Plasmodium falciparum map to the dimerization and receptor glycan binding sites of EBA-175.

Dataset

identifier:	1975549
description:	epitope description:VWECKKPYKLSTKDVCVPP antigen name:Erythrocyte binding antigen 175 host organism:Mus musculus BALB/c antibody name:R217
aggregation:	instance of dataset
availability:	available
primaryPublications:	23457550

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025616
landingPage:	http://www.iedb.org/assay/1975549

Publication

type:	Literature
publicationVenue:	PLoS One
dates:	2013

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum 3D7

Person

fullName:	Xavier Ambroggio Lubin Jiang Joan Aebig Harold Obiakor Jan Lukszo David L Narum

Data Type

method:	phage display

Study

name:	The epitope of monoclonal antibodies blocking erythrocyte invasion by Plasmodium falciparum map to the dimerization and receptor glycan binding sites of EBA-175.
description:	The Ph.D.-C7CTM, a disulfide constrained random 7-mer phage display library, was screened by panning on the mAb.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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