Abeta1-15/16 as a potential diagnostic marker in neurodegenerative diseases. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Abeta1-15/16 as a potential diagnostic marker in neurodegenerative diseases.

Dataset

identifier:	1973891
description:	epitope description:DAEFRHDSGYEVHHQ antigen name:Amyloid beta A4 protein host organism:Mus musculus antibody name:2B3
aggregation:	instance of dataset
availability:	available
primaryPublications:	23225274

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025621
landingPage:	http://www.iedb.org/assay/1973891

Publication

type:	Literature
publicationVenue:	Neuromolecular Med
dates:	2013

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Magdalena Nutu Philippe Bourgeois Henrik Zetterberg Erik Portelius Ulf Andreasson Sté phane Parent Francesco Lipari Sara Hall Radu Constantinescu Oskar Hansson Kaj Blennow

Data Type

method:	ELISA

Study

name:	Abeta1-15/16 as a potential diagnostic marker in neurodegenerative diseases.
description:	Longer and shorter peptides (A beta 1-16:DAEFRHDSGYEVHHQKL, A beta 1-17:DAEFRHDSGYEVHHQK, and A beta 1-14:DAEFRHDSGYEVHH) were also recognized but to a lower extent. A carboxypeptidase (CPB) present in fetal bovine serum (FBS), a component of the buffers used, degrades A beta 1-16 to A b 1-15, which is then detected by the A beta 1-15/16 assay.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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