Plasmodium berghei sporozoite challenge of vaccinated BALB/c mice leads to the induction of humoral immunity and improved function of CD8(+) memory T cells.

Title:

Plasmodium berghei sporozoite challenge of vaccinated BALB/c mice leads to the induction of humoral immunity and improved function of CD8(+) memory T cells.

Dataset

identifier:	1974372
description:	epitope description:PGGNNNNKNNNNDDSYIPSAEKILEFVKQI antigen name:Circumsporozoite (CS) protein, putative host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	23229763

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025615
landingPage:	http://www.iedb.org/assay/1974372

Publication

type:	Literature
publicationVenue:	Eur J Immunol
dates:	2013

Dimension

study type:	b cell assays
subject species:	Plasmodium berghei ANKA

Person

fullName:	Susanne Tartz Christina Deschermeier Silke Retzlaff Volker Heussler Peter Sebo Bernhard Fleischer Thomas Jacobs

Data Type

method:	biological activity

Study

name:	Plasmodium berghei sporozoite challenge of vaccinated BALB/c mice leads to the induction of humoral immunity and improved function of CD8(+) memory T cells.
description:	A heterologous prime/boost vaccination including the epitope induced sporozoite-specific inhibition. This inhibitory capacity increased to over 60% 21 days after second P. berghei challenge (on day 135).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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