The epitope of monoclonal antibodies blocking erythrocyte invasion by Plasmodium falciparum map to the dimerization and receptor glycan binding sites of EBA-175.

Title:

The epitope of monoclonal antibodies blocking erythrocyte invasion by Plasmodium falciparum map to the dimerization and receptor glycan binding sites of EBA-175.

Dataset

identifier:	1974327
description:	epitope description:NMVPLWR host organism:Mus musculus BALB/c antibody name:R256
aggregation:	instance of dataset
availability:	available
primaryPublications:	23457550

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025616
landingPage:	http://www.iedb.org/assay/1974327

Publication

type:	Literature
publicationVenue:	PLoS One
dates:	2013

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Xavier Ambroggio Lubin Jiang Joan Aebig Harold Obiakor Jan Lukszo David L Narum

Data Type

method:	phage display

Study

name:	The epitope of monoclonal antibodies blocking erythrocyte invasion by Plasmodium falciparum map to the dimerization and receptor glycan binding sites of EBA-175.
description:	The Ph.D.-C7CTM, a disulfide constrained random 7-mer phage display library, was screened by panning on the mAb. The selected peptides were to predict epitope residues on EBA-175 RII through structural and bioinformatic analysis.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.