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identifier: 1974422
description:
epitope description:DYEDRYYRE
antigen name:Major prion protein
host organism:Mus musculus PrP null
antibody name:6H4
aggregation:
instance of dataset
availability:
available
primaryPublications: 23469131
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1025620
landingPage: http://www.iedb.org/assay/1974422
type:
Literature
publicationVenue:
PLoS One
dates:
2013
study type: b cell assays
subject species: Homo sapiens
fullName:
Kentaro Masujin
Yuko Kaku-Ushiki
Ritsuko Miwa
Hiroyuki Okada
Yoshihisa Shimizu
Kazuo Kasai
Yuichi Matsuura
Takashi Yokoyama
method:
immunoprecipitation
name:
The N-terminal sequence of prion protein consists an epitope specific to the abnormal isoform of prion protein (PrP(Sc)).
description:
The epitope sequence was provided on the Prionics product web page [www.prionics.com].
The epitope-specific mAb bound sheep PrP Sc by immunoprecipitation. Positive reactivity included Chandler- and ME7-affected mouse brain homogenates.

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