Sub-domains of ricin's B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodies.

Title:

Sub-domains of ricin's B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodies.

identifier:	1974481
description:	epitope description:WHWDPYSGTEVK host organism:Mus musculus BALB/c antibody name:B/J F9
aggregation:	instance of dataset
availability:	available
primaryPublications:	22984492

study type:	b cell assays
subject species:

fullName:	Anastasiya Yermakova David J Vance Nicholas J Mantis

method:	biological activity

name:	Sub-domains of ricin's B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodies.
description:	The epitope was identified by phage-display. The epitope-reactive mAb neutralized ricin in a Vero cell cytotoxicity assay and partially (50%) blocked ricin attachment to cell surface receptors in a solid phase binding assay. The mAb did not protect THP-1 cells from ricin-induced apoptosis.

name:	iedb
homePage:	http://www.iedb.org

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