Effects of amino acid substitutions in the VP2 B-C loop on antigenicity and pathogenicity of serotype Asia1 foot-and-mouth disease virus.

Title:

Effects of amino acid substitutions in the VP2 B-C loop on antigenicity and pathogenicity of serotype Asia1 foot-and-mouth disease virus.

identifier:	1975134
description:	epitope description:D358 antigen name:Genome polyprotein host organism:Mus musculus BALB/c antibody name:1B4
aggregation:	instance of dataset
availability:	available
primaryPublications:	22963009

study type:	b cell assays
subject species:	Foot-and-mouth disease virus - type Asia 1 YS/CHA/05

fullName:	Mei Xue Haiwei Wang Wan Li Guohui Zhou Yabin Tu Li Yu

method:	immuno staining

name:	Effects of amino acid substitutions in the VP2 B-C loop on antigenicity and pathogenicity of serotype Asia1 foot-and-mouth disease virus.
description:	The epitope-specific mAb stained BHK-21 cells infected with wildtype virus. Reactivity was lost when the epitope residue was mutated to G or N. A non-reactive strain, Asia1/1/YZ/CHA/06, was recognized by the mAb when the epitope residue was introduced to the strain.

name:	iedb
homePage:	http://www.iedb.org

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