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identifier: 1977839
description:
epitope description:QLINTNGSWHIN
antigen name:Genome polyprotein
host organism:Mus musculus BALB/c
antibody name:AP33
aggregation:
instance of dataset
availability:
available
primaryPublications: 23458406
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1025723
landingPage: http://www.iedb.org/assay/1977839
type:
Literature
publicationVenue:
J Mol Biol
dates:
2013
study type: b cell assays
subject species: Hepatitis C virus
fullName:
Homer Pantua
Jingyu Diao
Mark Ultsch
Meredith Hazen
Mary Mathieu
Krista McCutcheon
Kentaro Takeda
Shailesh Date
Tommy K Cheung
Qui Phung
Phil Hass
David Arnott
Jo-Anne Hongo
David J Matthews
Alex Brown
Arvind H Patel
Robert F Kelley
Charles Eigenbrot
Sharookh B Kapadia
method:
biological activity
name:
Glycan shifting on hepatitis C virus (HCV) E2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.
description:
The epitope-specific antibody AP33 neutralized HCV genotype 1b (Con1).