| identifier: | 1977803 |
| description: |
epitope description:A: H43, K45, I47, T302, L303, P304, T329; B: V358, D359, G360, W361, K378, T381, Q382, K383, F385, D386, V392, I396
antigen name:Hemagglutinin
host organism:Mus musculus BALB/c
antibody name:C179
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
23552413 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1025765 |
| landingPage: |
http://www.iedb.org/assay/1977803 |
| type: |
Literature
|
| publicationVenue: |
J Virol
|
| dates: |
2013
|
| study type: | b cell assays |
| subject species: | Influenza A virus (A/Japan/305/1957(H2N2)) |
| fullName: |
Cyrille Dreyfus
Damian C Ekiert
Ian A Wilson
|
| method: |
bio-layer interferometry assay
|
| name: |
Structure of a classical broadly neutralizing stem antibody in complex with a pandemic H2 influenza virus hemagglutinin.
|
| description: |
The affinity of epitope-specific Fab C179 for the HA molecule was determined by bio-layer interferometry using an Octet Red instrument. Fab C179 binds to several group 1 subtypes, but does not bind to any influenza group 2 or influenza B (B/Florida/4/2006 and B/Malaysia/2506/2004) HAs tested.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |