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identifier: 1977790
description:
epitope description:A: H43, K45, I47, T302, L303, P304, T329; B: V358, D359, G360, W361, K378, T381, Q382, K383, F385, D386, V392, I396
antigen name:Hemagglutinin
host organism:Mus musculus BALB/c
antibody name:C179
aggregation:
instance of dataset
availability:
available
primaryPublications: 23552413
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1025765
landingPage: http://www.iedb.org/assay/1977790
type:
Literature
publicationVenue:
J Virol
dates:
2013
study type: b cell assays
subject species: Influenza A virus (A/Japan/305/1957(H2N2))
fullName:
Cyrille Dreyfus
Damian C Ekiert
Ian A Wilson
method:
bio-layer interferometry assay
name:
Structure of a classical broadly neutralizing stem antibody in complex with a pandemic H2 influenza virus hemagglutinin.
description:
The affinity of epitope-specific Fab C179 for the HA molecule was determined by bio-layer interferometry using an Octet Red instrument. Fab C179 binds to several group 1 subtypes, but does not bind to any influenza group 2 or influenza B (B/Florida/4/2006 and B/Malaysia/2506/2004) HAs tested.

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