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Title: Plasmodium falciparum synthetic LbL microparticle vaccine elicits protective neutralizing antibody and parasite-specific cellular immune responses.
identifier: 1976168
description:
epitope description:NANPNANPNANPNANPNANP
antigen name:Circumsporozoite (CS) protein
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 23481177
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1025677
landingPage: http://www.iedb.org/assay/1976168
type:
Literature
publicationVenue:
Vaccine
dates:
2013
study type: b cell assays
subject species: Plasmodium falciparum
fullName:
Thomas J Powell
Jie Tang
Mary E Derome
Robert A Mitchell
Andrea Jacobs
Yanhong Deng
Naveen Palath
Edwin Cardenas
James G Boyd
Elizabeth Nardin
method:
biological activity
name:
Plasmodium falciparum synthetic LbL microparticle vaccine elicits protective neutralizing antibody and parasite-specific cellular immune responses.
description:
Sera from mice immunized with the epitope neutralized recombinant P. berghei expressing circumsporozoite protein from P. falicparum. Neutralization was measured using the Transgenic Sporozoite Neutralization Assay (TSNA). Neutralization was greatly decreased without the Pam3Cys conjugate.

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